INTERREG SPAIN-PORTUGAL (POCTEP). PORTUGAL.
Title of the project: "Marine compounds open new therapeutic avenues for osteoarthritis"
Description of the project: We propose to investigate the therapeutic potential of novel bioactive natural marine compounds, as novel Disease Modifying Drugs (DMDs) in the treatment of OA, with potential direct translational application. The protective effect of marine bioactive compounds will be explored in terms of disease modifying responses using a human in vitro OA model mimicking OA conditions, as a first approach to high throughput screening, followed by pre-clinical testing in vivo in OA mouse model for validation.
Partner sought: Blue bioresources and biotechnology; Marine biotecnology; Marine Natural Products Chemistry; biofermentation; Microalgae and microbiology; Bioassay screening of secondary metabolites from Portugal: Alto Minho, Cávado, Ave, Área Metropolitana do Porto; Alto Tâmega, Tâmega e Sousa, Douro, Terra de Trás-os- Montes, beiras e Serra da Estrela, Beira Baixa Viseu Dão-Lafões, Região de Aveiro, Região de Coimbra, Médio Tejo, Região de Leiria, Oeste, Alto Alentejo, Alentejo Central, Baixo Alentejo, Alentejo Litoral, Algarve. España: A Coruña, Lugo, Ourense, Pontevedra, León, Salamanca, Zamora, Valladolid, Ávila, Cáceres, Badajoz, Huelva, Cádiz, Córdoba, Sevilla.
Publicado por europa en noviembre 24, 2015